白明义
单位：山东大学
电话：0532-58630881
E-Mail：baimingyi@sdu.edu.cn
个人简介
白明义，2000年在山西农业大学本科毕业，2003年沈阳农业大学获得硕士学位，2007年在中国科学院植物研究所获得博士学位，然后在美国Carnegie Institution for Science做博士后研究，于2014年5月回到山东大学工作。现为山东大学“齐鲁学者”特聘教授，国家第五批“海外国家高层次青年人才”获得者和山东省“杰出青年基金”获得者。主要从事激素调控植物生长发育和环境适应性的分子机制研究。近年来先后在Nature Communications, Plant Cell, New Phytologist等杂志发表多篇高水平的研究论文，在相关领域产生较大影响。兼任山东植物生理学会常务理事，植物学报编委。
教学
主讲《植物生理学》，《植物生物学》，《生命科学导论》等专业必修课程，同时开设《植物激素》双语课程和参与《Topic in molecular genetics》的全英文课程讲授，每年平均课时48学时以上，讲授的课程受到学生的广泛好评。在研究生教学方面，按照因材施教和个性化培养理念，积极参与制定执行研究生培养计划，统筹安排实践与科研活动，培养研究生的创新意识和创新能力，开展创新性研究工作。指导的学生获得“山东大学优秀博士学位论文”和“山东省优秀博士学位论文”。
研究方向
白明义课题组主要以模式植物拟南芥和粮食作物小麦为材料，利用遗传学、生物化学、基因组学、蛋白组学等手段研究油菜素甾醇调控植物碳氮平衡利用的分子机理研究。具体来讲我们研究以下五个方面的内容：
（1）油菜素甾醇调控活性氧代谢影响植物发育和环境适应的分子机制
（2）油菜素甾醇调控植物淀粉-糖代谢和糖信号转导的分子机制；
（3）油菜素甾醇调控植物氮吸收、利用和信号转导的分子机制；
（4）油菜素甾醇调控植物碳-氮平衡利用的分子机制；
（5）解析油菜素甾醇调控小麦株型和碳-氮平衡利用的分子机理，为培育高产优质小麦新品种奠定理论基础。
主持项目
1. 2021-2024 糖调控植物气孔发育的分子机理研究，国家自然科学基金委面上项目，主持；
2. 2019-2022过氧化氢和油菜素内酯调控植物根尖干细胞维持与分化的分子机制，国家自然科学基金委面上项目，主持；
3. 2019-2021 小麦高产、优质基因的基因编辑与种质创新，山东省农业良种工程，课题主持；
4. 2018-2020 大豆、棉花和苜蓿干细胞维持与分化关键基因挖掘及应用，山东省自然科学基金重大基础研究项目，课题主持；
5. 2017-2020油菜素内酯调控植物叶腋分生组织起始和分化的分子机制研究，国家自然科学基金委面上项目，主持；
6. 2017-2020 植物激素和株型调控，山东省杰出青年基金，主持；
7. 2015-2018油菜素内酯和生物钟协调控制植物生长和免疫抗病平衡的分子机制，国家自然科学基金面上项目，主持，
8. 2015-2017 微环境调控植物生长点干细胞中心维持与重建的分子网络，国家重大基础研究计划，课题主持。
近五年5篇代表性研究论文
1. Honglei Wang, Chao Han, Jia-Gang Wang, Xiaoqian Chu, Wen Shi, Lianmei Yao, Jie Chen , Wei Hao, Zhiping Deng, Min Fan, and Ming-Yi Bai*. (2022). Regulatory functions of cellular energy sensor SnRK1 for nitrate signalling through NLP7 repression. Nature Plants. 8(9):1094-1107. 【Nature Plants专文评述】
2. Yanchen Tian, Min Fan, Zhaoxia Qin, Hongjun Lv, Minmin Wang, Zhe Zhang, Wenying Zhou, Na Zhao, Xiaohui Li, Chao Han, Zhaojun Ding, Wenfei Wang, Zhi-Yong Wang and Ming-Yi Bai*. (2018). Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor. Nature Communications, 9:1063. 【高被引论文】
3. Chao Han, Wenbo Hua, Jinge Li, Yan Qiao, Lianmei Yao, Wei Hao, Ruizi Li, Min Fan, Geert De Jaeger, Wenqiang Yang and Ming-Yi Bai*. (2022). TOR promotes guard cell starch degradation by regulating the activity of β-AMYLASE1 in Arabidopsis. The Plant Cell. 34(3):1038-1053. 【The Plant Cell专文评述】【F1000推荐】
4. Jin-Ge Li, Min Fan, Wenbo Hua, Yanchen Tian, Lian-Ge Chen, Yu Sun, Ming-Yi Bai*. (2020) Brassinosteroid and hydrogen peroxide interdependently induce stomatal opening by promoting guard cell starch degradation. The Plant Cell. 32: 984-999. 【The Plant Cell专文评述】
5. Xiaoqian Chu#, Jia-Gang Wang#, Mingzhe Li, Shujuan Zhang, Yangyang Gao, Min Fan, Chao Han, Fengning Xiang, Genying Li, Yong Wang, Xiang Yu, Chenbing Xiang, and Ming-Yi Bai*. (2021) HBI transcription factor-mediated ROS homeostasis regulates nitrate signal transduction. The Plant Cell. 33(9): 3004-3021.【F1000推荐】
图.白明义课题组近5年学术成绩汇总
课题组所有论文
2022年
1. Honglei Wang, Chao Han, Jia-Gang Wang, Xiaoqian Chu, Wen Shi, Lianmei Yao, Jie Chen , Wei Hao, Zhiping Deng, Min Fan, and Ming-Yi Bai*. (2022). Regulatory functions of cellular energy sensor SnRK1 for nitrate signalling through NLP7 repression. Nature Plants. 8(9):1094-1107. 【Nature Plants专文评述】
2. Chao Han, Wenbo Hua, Jinge Li, Yan Qiao, Lianmei Yao, Wei Hao, Ruizi Li, Min Fan, Geert De Jaeger, Wenqiang Yang and Ming-Yi Bai*. (2022). TOR promotes guard cell starch degradation by regulating the activity of β-AMYLASE1 in Arabidopsis. The Plant Cell. 34(3):1038-1053. 【The Plant Cell专文评述】【F1000推荐】
3. Wen Shi, Lingyan Wang, Lianmei Yao, Wei Hao, Chao Han, Min Fan, Wenfei Wang, and Ming-Yi Bai*. (2022). Spatially patterned hydrogen peroxide orchestrates stomatal development in Arabidopsis. Nature Communications. 13(1):5040.
4. Chao Han, Yan Qiao, Lianmei Yao, Wei Hao, Yue Liu, Wen Shi, Min Fan and Ming-Yi Bai*. (2022). TOR and SnRK1 fine tune SPEECHLESS transcription and protein stability to optimize stomatal development in response to exogenously supplied sugar. New Phytologist. 234(1):107-121.
5. Yanchen Tian, Na Zhao, Minmin Wang, Wenying Zhou, Jieqiong Guo, Chao Han, Chuanen Zhou, Wenfei Wang, Shuang Wu, Wenqiang Tang, Min Fan and Ming-Yi Bai*. (2022). Integrated regulation of periclinal cell division by transcriptional module of BZR1-SHR in Arabidopsis roots. New Phytologist. 233(2):795-808.
6. Mei Wang, Meng Wang, Min Zhao, Mengcheng Wang, Shupeng Liu, Yanchen Tian, Byeongho Moon, Chaochao Liang, Chunlong Li, Weiming Shi, Ming-Yi Bai, Shuwei Liu, Wei Zhang, Inhwan Hwang, and Guangmin Xia. (2022). TaSRO1 plays a dual role in suppressing TaSIP1 to fine tune mitochondrial retrograde signalling and enhance salinity stress tolerance. New Phytologist. 236(2):495-511.
7. Guohua Chai, Guang Qi, Dian Wang, Yamei Zhuang, Hua Xu, Zetao Bai, Ming-Yi Bai, Ruibo Hu, Zeng-Yu Wang, Gongke Zhou and Yingzhen Kong. (2022). The CCCH zinc finger protein C3H15 negatively regulates cell elongation by inhibiting brassinosteroid signaling. Plant Physiology. 189(1):285-300.
8. Meng Li, Pengxue Li, Chunhua Wang, Huimin Xu, Mengxue Wang, Yanli Wang, Xufang Niu, Mengyuan Xu, Hong Wang, Yaxin Qin, Wenqiang Tang, Ming-Yi Bai, Wenfei Wang, and Shuang Wu*. (2022). Brassinosteroid signaling restricts root lignification by antagonizing SHORT-ROOT function in Arabidopsis. Plant Physiology. 190(2):1182-1198.
9. Jie Wu, Ying Song, Zi-Sheng Zhang, Jing-Xian Wang, Xuan Zhang, Jian-Ye Zang, Ming-Yi Bai, Lin-Hui Yu, and Cheng-Bin Xiang*. (2022). GAF domain is essential for nitrate-dependent AtNLP7 function. BMC Plant Biology. 22(1):366.
2021年
10. Xiaoqian Chu#, Jia-Gang Wang#, Mingzhe Li, Shujuan Zhang, Yangyang Gao, Min Fan, Chao Han, Fengning Xiang, Genying Li, Yong Wang, Xiang Yu, Chenbing Xiang, and Ming-Yi Bai*. (2021) HBI transcription factor-mediated ROS homeostasis regulates nitrate signal transduction. The Plant Cell. 33(9): 3004-3021.【F1000推荐】
11. Na Zhao, Min Zhao, Yanchen Tian, Yichuan Wang, Chao Han, Min Fan, Hongwei Guo and Ming-Yi Bai* (2021). Interaction between BZR1 and EIN3 mediates signalling crosstalk between brassinosteroids and ethylene. New Phytologist. 232(6):2308-2323.
12. Xiaoqian Chu, Mingzhe Li, Shujuan Zhang, Min Fan, Chao Han, Fengning Xiang, Genying Li, Yong Wang, Cheng-bin Xiang, Jia-Gang Wang* and Ming-Yi Bai*. (2021). HBI1-TCP20 interaction positively regulates the CEPs-mediated systemic nitrate acquisition. Journal of Integrative Plant Biology. 63(5): 902-912.
13. Yiming Kong, Zhe Meng, Hongfeng Wang, Yan Wang, Yuxue Zhang, Limei Hong, Rui Liu, Min Wang, Jing Zhang, Lu Han, Ming-Yi Bai, Xiaolin Yu, Fanjiang Kong, Kirankumar S Mysore, Jiangqi Wen, Peiyong Xin, Jinfang Chu and Chuanen Zhou. (2021). Brassinosteroid homeostasis is critical for the functionality of the Medicago truncatula pulvinus. Plant Physiology. 185(4):1745-1763.
14. Guang Qi, Huan Chen, Dian Wang, Hongyuan Zheng, Xianfeng Tang, Zhengzheng Guo, Jiayu Cheng, Jian Chen, Yiping Wang, Ming-Yi Bai, Fengquan Liu, Daowen Wang and Zheng Qing Fu. (2021). The BZR1-EDS1 module regulates plant growth-defense coordination. Molecular Plant. 4(12):2072-2087.
15. Lingyan Wang, Ping Yu, Jinyang Lyu, Yanfei Hu, Chao Han, Ming-Yi Bai and Min Fan*. (2021). BZR1 Physically Interacts with SPL9 to Regulate the Vegetative Phase Change and Cell Elongation in Arabidopsis. International Journal of Molecular Sciences. 22(19):10415
2020年
16. Jin-Ge Li, Min Fan, Wenbo Hua, Yanchen Tian, Lian-Ge Chen, Yu Sun, Ming-Yi Bai*. (2020) Brassinosteroid and hydrogen peroxide interdependently induce stomatal opening by promoting guard cell starch degradation. The Plant Cell. 32: 984-999. 【The Plant Cell专文评述】
17. Chao Han, Yue Liu, Wen Shi, Yan Qiao, Lingyan Wang, Yanchen Tian, Min Fan, Zhiping Deng, On Sun Lau, Geert De Jaeger and Ming-Yi Bai*. (2020) KIN10 promotes stomatal development through stabilization of the SPEECHLESS transcription factor. Nature Communications, 11:4214
18. Lingyan Wang, Yanchen Tian, Wen Shi, Ping Yu, Yanfei Hu, Jinyang Lv, Chunxiang Fu, Min Fan* and Ming-Yi Bai*. (2020) The miR396-GRFs module mediates the prevention of photo-oxidative damage by brassinosteroids during seedling de-etiolation in Arabidopsis. The Plant Cell. 32: 2525-2542.
19. Ke Liao, Yu-Jun Peng, Li-Bing Yuan, Yang-Shuo Dai, Qin-Fang Chen, Lu-Jun Yu, Ming-Yi Bai, Wen-Qing Zhang, Li-Juan Xie, Shi Xiao*. (2020) Brassinosteroids antagonize jasmonates-activated plant defense responses through BRI1-EMS-SUPPRESSOR1. Plant Physiology, 182:1066-1082.
20. QiQi Zhang, JiaGang Wang, LingYan Wang, JunFang Wang, Qun Wang, Ping Yu, Ming-Yi Bai and Min Fan*. (2020) Gibberellin repression of axillary bud formation in Arabidopsis by modulation of DELLA-SPL9 complex activity. Journal of Integrative Plant Biology. 62:421-432.
21. Minmin Wang, Yanchen Tian, Chao Han, Chuanen Zhou, Ming-Yi Bai and Min Fan*. (2020). Phospho-mutant activity assays provide evidence for the negative regulation of transcriptional regulator PRE1 by phosphorylation. International Journal of Molecular Sciences. 21: 9183
2019年
22. Qiang Ge, Yuanyuan Zhang, Yunyuan Xu, Ming-Yi Bai, Wei Luo, Bo Wang, Yuda Niu, Yuan Zhao, Shanshan Li, Yuxiang Weng, Zhiyong Wang, Qian Qian, Kang Chong*. (2019) Cyclophilin OsCYP20-2 with a novel variant integrates defense and cell elongation for chilling response in rice. New Phytologist. 225: 2453-2467
23. Li Song, Wei Chen, Biao Wang, Qiu-Ming Yao, Babu Valliyodan, Ming-Yi Bai, Ming-Zhe Zhao, Heng Ye, Zhi-Yong Wang, Henry T Nguyen*. (2019) GmBZL3 acts as a major BR signaling regulator through crosstalk with multiple pathways in Glycine max. BMC plant biology. 19(1):86.
24. Shuo Li, Nan Wang, Dandan Ji, Wenxiao Zhang, Ying Wang, Yanchong Yu, Shizhen Zhao, Menghua Lyu, Juanjuan You, Yangyang Zhang, Luli Wang, Xiaofang Wang, Zhenhua Liu, Jianhua Tong, Langtao Xiao, Ming-Yi Bai, Fengning Xiang*. (2019) A GmSIN1/GmNCED3s/GmRbohBs feed-forward loop acts as a signal amplifier that regulates root growth in soybean exposed to salt stress. The Plant Cell. 31(9): 2107-2130.
25. Yang Zhao, Rong Liu, Yiteng Xu, Minmin Wang, Jing Zhang, Ming-Yi Bai, Chao Han, Fengning Xiang, Zeng-Yu Wang, Kirankumar S. Mysore, Jiangqi Wen, and Chuanen Zhou*. (2019) AGLF provides C-function in floral organ identity through transcriptional regulation of AGAMOUS in Medicago truncatula. Proc Natl Acad Sci U S A. 116(11): 5176-5181
2018年
26. Yanchen Tian, Min Fan, Zhaoxia Qin, Hongjun Lv, Minmin Wang, Zhe Zhang, Wenying Zhou, Na Zhao, Xiaohui Li, Chao Han, Zhaojun Ding, Wenfei Wang, Zhi-Yong Wang and Ming-Yi Bai*. (2018) Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor. Nauture Communications, 9:1063. 【高被引论文】
27. Huiyu Tian, Bingsheng Lv, Tingting Ding, Ming-Yi Bai* and Zhaojun Ding*. (2018) Auxin-BR Interaction Regulates Plant Growth and Development. Frontiers in Plant Science. 8:2256
2016年
28. Min Fan, Minmin Wang and Ming-Yi Bai*. (2016) Diverse roles of SERK family genes in plant growth, development and defense response. Science China Life Sciences. 59(9): 889-896
29. Zhenhua Liu, Juan Li, Long Wang, Qiang Li, Qing Lu, Yanchong Yu, Shuo Li, Ming-Yi Bai, Yuxin Hu and Fengning Xiang*. (2016). Repression of callus initiation by the miRNA-directed interaction of auxin–cytokinin in Arabidopsis thaliana. The Plant Journal. 87(4): 391-402
2014年之前
1. Wen-Fei Wang, Ming-Yi Bai, and Zhi-yong Wang*. (2014) The brassinosteroid signaling network - a paradigm of signal integration. Current Opinion in Plant Biology. 21:147-153.
2. Min Fan#, Ming-Yi Bai#, Jung-Gun Kim, Tina Wang, Eunkyoo Oh, Lawrence Chen, Chan Ho Park, Seung-Hyun Son, Seong-Ki Kim, Mary Beth Mudgett and Zhi-Yong Wang*. (2014). The bHLH Transcription Factor HBI1 Mediates the Trade-Off between Growth and Pathogen-Associated Molecular Pattern–Triggered Immunity in Arabidopsis. The Plant Cell. 26(2): 828-41. (#equal contribution).
3. Eunkyoo Oh, Jia-Ying Zhu, Ming-Yi Bai, Rafael Augusto Arenhart, Yu Sun and Zhi-Yong Wang*. (2014). Cell elongation is regulated through a central circuit of interacting transcription factors in the Arabidopsis hypocotyl. Elife. 3:e03031
4. Cui Zhang, Ming-Yi Bai, Kang Chong*. (2014). Brassinosteroid-mediated regulation of agronomic traits in rice. Plant Cell Reports. 33(5): 683-696.
5. Chunming Wang, Jian-Xiu Shang, Qi-Xiu Chen, Juan A. Oses-Prieto, Ming-Yi Bai, Yihong Yang, Min Yuan, Yu-Lan Zhang, Cong-Cong Mu, Zhiping Deng, Chuang-Qi Wei, Alma L. Burlingame, Zhi-Yong Wang and Ying Sun*. (2013). Identification of BZR1-interacting Proteins as Potential Components of the Brassinosteroid Signaling Pathway in Arabidopsis through Tandem Affinity Purification. Molecular & Cellular Proteomics. 12(12): 3653-3665.
6. Ming-Yi Bai, Jian-Xiu Shang, Eunkyoo Oh, Yang Bai, Min Fan, Rodolfo Zentella, Tai-Ping Sun, and Zhi-Yong Wang*. (2012). Brassinosteroid, Gibberellin and Phytochrome Impinge on a Common Transcription Module in Arabidopsis. Nature Cell Biology. 14: 810-817.
7. Ming-Yi Bai, Min Fan, Eunkyoo Oh, and Zhi-Yong Wang*. (2012). A Triple Helix-Loop-Helix/Basic Helix-Loop-Helix Cascade Controls Cell Elongation Downstream of Multiple Hormonal and Environmental Signaling Pathways in Arabidopsis. The Plant Cell. 24: 4917-4929.
8. Zhi-Yong Wang*, Ming-Yi Bai, Eunkyoo Oh, Jia-Ying Zhu. (2012). Brassinosteroid Signaling Network and Regulation of Photomorphogenensis. Annual Review of Genetics. 46: 701-724.
9. Joshua M. Gendron, Jiang-Shu Liu, Min Fan, Ming-Yi Bai, Stephan Wenkel, Patricia S. Springer, M.K. Barton, Zhi-Yong Wang*. (2012). Brassinosteroids Regulate Plant Architecture by Repressing Organ Boundary Identity Genes. Proc. Natl. Acad. Sci. 109 (51): 21152-21157.
10. Xi-Ying Fan, Yu Sun, Dong-Mei Cao, Ming-Yi Bai, Xiao-Min Luo, Chuangqi Wei, Hongjuan Yang, Shengwei Zhu, Ying Sun, Kang Chong and Zhi-Yong Wang*. (2012). BZS1, a B-box Protein, Promotes Photomorphogenesis Downstream of both Brassinosteroid and Light Signaling Pathways. Molecular Plant. 5 (3): 65-74.
11. Feng-Ru Wang, Ming-Yi Bai, Zhiping Deng, Oses-Priqeto JA, Burlingame AL, Tie-Gang Lu, Kang Chong, Zhi-Yong Wang*. (2010). Proteomic Study Identifies Proteins Involved in Brassinosteroid Regulation of Rice Growth. Journal of Integrative Plant Biology. 52 (12): 1075-1085.
12. Yu Sun, Xi-Ying Fan, Dong-Mei Cao, Wenqiang Tang, Hun He, Jia-Ying Zhu, Jun-Xian He, Ming-Yi Bai, Shen-Wei Zhu, Eunkyoo Oh, Sunita Patil, Tae-Wuk Kim, Ji H, Wong WH, Rhee SY, Zhi-Yong Wang*. (2010). Integration of Brassinosteroid Signal Transduction with the Transcription Network for Plant Growth Regulation in Arabidopsis. Developmental Cell. 19(5:) 756-777.
13. Li-Ying Zhang#, Ming-Yi Bai#, Jianxia Wu#, Jia-Ying Zhu, Hao Wang, Zhiguo Zhang, Wenfei Wang, Yu Sun, Jun Zhao, Xuehui Sun, Hongjuan Yang, Yunyuan Xu, Soo-Hwan Kim, Shozo Fujioka, Wen-Hui Lin, Kang Chong, Tiegang Lu, Zhi-Yong Wang*. (2009). Antagonistic HLH/bHLH Transcription Factors Mediate Brassinosteroid Regulation of Cell Elongation and Plant Development in Rice and Arabidopsis. The Plant Cell. 21(12): 3767-3780 (#equal contribution).
14. Zhi-Yu Peng, Xin Zhou, Linchuan Li, Xiangchun Yu, Hongjiang Li, Zhiqiang Jiang, Guangyu Cao, Ming-Yi Bai, Cingchun Wang, Caifu Jiang, Haibin Lu, Xianhui Hou, Lijia Qu, Zhi-Yong Wang, Jianru Zuo, Xiangdong Fu, Zhen Su, Songgang Li, Hongwei Guo*. (2009). Arabidopsis Hormone Database: a Comprehensive Genetic and Phenotypic Information Database for Plant Hormone Research in Arabidopsis. Nucleic Acids Research. 37, D975-D982.
15. Ming-Yi Bai, Li-Ying Zhang, Srinicas S. Gampala, Sheng-Wei Zhu, Wen-Yuan Song, Kang Chong*, Zhi-Yong Wang*. (2007). Functions of OsBZR1 and 14-3-3 Proteins in Brassinosteroid Signaling in Rice. Proc. Natl. Acad. Sci. 104 (34): 13839-13844.
16. Srinivas S Gampala, Tae-Wuk Kim, Jun-Xian He, Wenqiang Tang, Zhiping Deng, Ming-Yi Bai, Shenheng Guan, Sylvie Lalonde, Ying Sun, Joshua M, Gendron, Huanjing Chen, Nakako Shibagaki, Robert J Ferl, David Ehrhardt, Kang Chong, Alma L Burlingame, Zhi-Yong Wang*. (2007). An Essential Role for 14-3-3 Proteins in Brassinosteroid Signal Transduction in Arabidopsis. Developmental Cell. 13(2): 177-189.
17. Ming Xu, Ming-Yi Bai and Yutang Wei. (2007). Changes in Endogenous Hormone between B. campestris ssp. Chinensis Var. purpurea Hort. CMS Lines and Their Maintainer Line at Different Development Stages. Acta Agriculturae Boreali-Occidentalis Sinica. 16(3): 124-127, 135.
18. Zhi-Yong Wang*, Qiaomei Wang, Kang Chong, Fengru Wang, Lei Wang, Ming-Yi Bai, Chengguo Jia. (2006). The Brassinosteroid Signal Transduction Pathway. Cell Research. 16, 427-434.
19. Ming Xu*, Yutang Wei, Ming-Yi Bai. (2006). Cytomorphological Studies on Anther Development of Radish Cytoplasmic Male Sterile Llines in Purple Caitai. Acta Agriculturae Boreali-Sinica, 21:58-62.
20. Ming Xu*, Ming-Yi Bai and Yutang Wei. (2003). Transfer Male Sterile Gene of Chinese Cabbage toInbred Line 97A407. China Vegetable. 2:8-10.
